Percent of ICF
65
Percent of ECF
35
Percent of Tissue fluid
25
Percent of blood plasma and lymph
8
Percent of other
2
Gains of water mL
2500ml per day
Loss of water per day
2500ml per day
Insensible water loss
Expired air and cutaneous transpiration
Obligatory water loss
Insensible loss + sweat + fecal moisture + minimum urine output
Homeostatic mechanism of high osmolarity
Osmoreceptors in hypothalamus detect
Hypothalamus control center
ADH from posterior pituitary acts on DCT and CD and stimulates thirst center
Thirst center stimulated by
Angiotensin and ADH
Does thirst center increase or decrease blood osmolarity
Decrease
Aldosterone function
Increases water reabsorption PLUS salt
ADH function
Just water reabsorption
Problems with infants and dehydration main concern
Hypovolemia
Fluid sequestration major danger
Circulatory shock due to low blood volume
Pulmonary edema due to
Left ventricle heart failure
Systemic edema due to
Right ventricle heart failure
What makes you less thirsty?
Increased osmolarity
Why is fluid loss more problematic in infants
High body surface area to volume ratio
All electrolytes
Na, K, Ca, Mg, Cl, Phosphate
What is the principal cation of the ECF
Sodium
Where is sodium in the cell?
ECF
Where is potassium in the cell?
ICF