Nerve impulse/buzz
Action potential
Resting neuron
Negative inside, positive outside
Resting membrane potential?
-70 mV
What ions are outside/inside neuron?
Sodium outside, potassium inside
Sodium potassium pump
Protein in neuron membrane, pumps 3 Na out, 2 K in
What does the sodium potassium pump create
Electrochemical gradient, the difference in positive/negative
Voltage gated channels
Majority of membrane channels, they open and close in response to voltage change
What channel opens at -55 mV?
Na
Graded potential (localized)
When only a few channels open and a bit of sodium enters the cell
Threshold for action potential
-55mV
What happens when it hits -55mV?
All the sodium channels open and positive sodium ions rush in, depolarizing the cell
What is the result of an action potential
Sends an electrical signal down the axon
Repolarization
Voltage gated potassium ion channels open to let potassium ions flow out to rebalance charges
Refractory period
When an axon is in the middle of an action potential and all the ion channels are open
Peak depolarization
40mV
Weak stimulus
Triggers less frequent action potentials, like if your brain is telling you to do something
Action potential speed
Faster in reflex pathways, slower in glands, gut, blood vessels
Saltatory conduction
When a action potential travels down the myelin sheath, it’s much faster
What happens when an action potential reaches the end of the neuron?
Hits the synapse which then translates it into a different type of signal
Electrical synapse
Immediate signal, like a group text
Chemical synapse
Takes more time to be received and read but used more often and easier to control, sending signal to only certain people i.e. direct message
Why is electrical synapse so fast
Send an ion current flowing directly from one neuron to another using gap junctions. Signal is never converted from the pure electrical state
When is electrical synapse used?
Muscle cell of heart
Chemical synapses use what instead of raw electricity
Neurotransmitters (chemical signals) that diffuse across synaptic gap