Naloxone

Question 1

Presentation of Naloxone

Answer 1

0.4mg in 1ml amp

2mg in 5ml (prepared syringe)

Question 2

Pharmacology of Naloxone

Answer 2

Narcotic antagonist

Actions:
Prevents or reverses the effects of narcotics

Question 3

Metabolism of Naloxone

Answer 3

By the liver

Question 4

Naloxone Indications

Answer 4

Altered conscious state and respiratory depression secondary to administration of narcotic or related drugs

Question 5

Naloxone Contraindications

Answer 5

Nil of significance

Question 6

Naloxone Precautions

Answer 6

• If pt is physically dependant on narcotics, be prepared to deal with combative pt after administration
• Neonates

Question 7

Route of Administration of Naloxone

Answer 7

IM

IV

Question 8

Side Effects of Naloxone

Answer 8

• Symptoms of narcotic withdrawl
• Agitation
• Nausea and vomiting
• Dilatation of pupils, excessive lacrimation
• Sweating, gooseflesh, tremor
• Convulsions

Question 9

Effects of Naloxone

Answer 9

IV
Onset: 1-3min
Duration: 30-45min

IM
Onset: 1-3min
Duration: 30-45min