Salbutamol

Question 1

Presentation of Salbutamol

Answer 1

• 5mg in 2.5ml neb/polyamp
• 500mcg in 1ml amp
• 5mg in 5ml amp
• pMDI

Question 1

Pharmacology of Salbutamol

Answer 1

Synthetic Beta-adrenergic stimulant with primarily Beta 2 effects

Question 2

Pharmacology of Salbutamol (actions)

Answer 2

Causes bronchodilatation

Question 3

Metabolism of Salbutamol

Answer 3

By the liver and excreted by the kidneys

Question 3

Salbutamol Indications

Answer 3

Respiratory distress with suspected bronchospasm:

• COPD
• Oleoresin capsicum spray exposure
• Pulmonary oedema
• Asthma
• Smoke inhalation
• Severe allergic reactions

Question 4

Salbutamol Contraindications

Answer 4

Nil of significance

Question 4

Salbutamol Precautions

Answer 4

• Between doses, oxygen must be administered continuously

- Large doses of IV Salbutamol have been reported to cause intracellular metabolic acidosis

Question 5

Route of Administration of Salbutamol

Answer 5

pMDI
Nebulised
IV
IV infusion
ET

Question 5

Side Effects of Salbutamol

Answer 5

Sinus tachycardia

Muscle tremor

Question 6

Effects of Salbutamol

Answer 6

Nebulised
Onset: 5-15min
Duration: 15-50min

IV
Onset:1-2min
Duration: 30-60min