Prochlorperazine

Question 1

Presentation of Prochlorperazine

Answer 1

12.5mg in 1ml amp

Question 2

Pharmacology of Prochlorperazine

Answer 2

Anti-emetic

Action:
- Acts on several central neuro-transmitter systems

Question 3

Metabolism of Prochlorperazine

Answer 3

Metabolised by the liver and excreted by the kidneys

Question 4

Prochlorperazine Indications

Answer 4

Treatment or prophylaxis of nausea/vomiting for:

• Motion sickness
• Vertigo
• Planned areomedical evacuation
• Headache irrespective of nausea/vomiting
• Known allergy or contraindication to Metoclopramide administration

Question 5

Prochlorperazine Contraindications

Answer 5

• Previous hypersensitivity
• CNS depression
• Circulatory collapse
• Children

Question 6

Prochlorperazine Precautions

Answer 6

• Hypotension
• Epilepsy
• Pts effected by alcohol or on anti-depressants

Question 7

Route of Administration of Prochlorperazine

Answer 7

IM

Question 8

Side Effects of Prochloperazine

Answer 8

• Blurred vision
• Sinus tachycardia
• Skin rash
• Hypotension
• Extrapyramidal reactions
• Drowsiness

Question 9

Effects of Prochlorperazine

Answer 9

IM
Onset: 20min
Peak: 40min
Duration: 6hrs