What are the characteristics of the normal liver on radiographs?
-in the cranial abdomen mostly under the costal arch
-cranial to stomach
-size assessed using the gastric axis
How is the gastric axis used to assess liver size?
-normal gastric axis is parallel to the ribs
-a large liver will push the stomach caudal and change the gastric axis
What is shown in these images?
normal liver; normal gastric axis
What are the characteristics of normal liver on ultrasound?
-smooth, sharp margins
-coarse echotexture
-portal vein walls are hyperechoic
-hypoechoic to the spleen
What are the characteristics of the biliary tree on ultrasound?
-gall bladder typically contains anechoic bile
-presence of sludge is normal in dogs
-normally do not see intrahepatic bile ducts
-common bile duct is small; normally seen in cats
What is shown in these images?
normal ultrasound of the liver
What is shown in these images?
ultrasound of the gall bladder:
-top: anechoic bile
-bottom: sludge (normal in dogs)
How does generalized liver enlargement differ from focal liver enlargement?
*generalized:
-enlargement of the whole liver with maintenance of normal shape
*focal:
-enlargement of a portion of the liver
-alters liver shape in area of enlargement
-due to a nodule or mass
-can be singular or multiple; focal or multifocal
What are the differentials for generalized liver enlargement?
*metabolic:
-diabetes mellitus
-hyperadrenocorticism
-hepatic lipidosis
*infectious/inflammatory:
-hepatitis/cholangiohepatitis
*infiltrative neoplasia:
-round cell
*vascular congestion:
-right heart failure
-caval syndrome
What are the differentials for focal liver enlargement?
*nodular regeneration (most common in dogs)
*neoplasia
-primary or metastatic
-benign or malignant
*abscess/granuloma
*cyst
What are the radiograph findings in generalized hepatomegaly?
-enlarged liver with maintained shape
-extends beyond costal arch
-displacement of stomach caudally
-rounded margins
What are the ultrasound findings in generalized hepatomegaly?
-may appear normal aside from size
-diffusely hypo- or hyper-echoic
-may see nodules
-may see distended hepatic veins in cases of congestion
What is shown in these images?
*generalized hepatomegaly:
-extends past costal arch
-gastric axis no longer parallel with ribs; pylorus pushed caudal
What can cause generalized hepatomegaly to appear diffusely hyperechoic on ultrasound?
*metabolic/endocrine:
-steroid hepatopathy/hyperadrenocorticism
-endocrine disease/diabetes mellitus
-hepatic lipidosis
-vacuolar hepatopathy
*fibrosis
*chronic hepatitis
*infiltrative disease/round cell neoplasia
What is shown in this image?
diffusely hyperechoic liver
What can cause generalized hepatomegaly to appear diffusely hypoechoic on ultrasound?
*acute hepatitis
*congestion
-right heart failure
-caval syndrome
*infiltrative disease/round cell neoplasia
What is shown in this image?
diffusely hypoechoic liver
What is shown in these images?
generalized hepatomegaly:
-pendulous abdomen with no fluid accumulation
-likely hyperadrenocorticism/cushing’s
What is shown in this image?
generalized hepatomegaly
What is shown in these images?
*generalized hepatomegaly:
-hepatic congestion and ascites
-enlargement of hepatic vein and caudal vena cava
What are the imaging findings in the event of a liver mass/nodule?
-nodule or mass affecting the liver
-change in shape of liver margins
-possible peritoneal effusion
-mass effect; soft tissue opaque structure displacing the stomach/gastric axis
How is a hepatic mass differentiated from a splenic mass on radiographs?
-hepatic masses tend to be cranial to the stomach; exception is a pedunculated liver mass
-may see fat-opaque fascial plane between liver lobe and spleen
What is shown in these images?
*focal hepatomegaly:
-stomach displaced to the left on VD view
-right kidney is deviated
What is shown in these images?
Left: normal; normal margin
Middle: diffuse infiltrate; rounded margin
Right: focal mass; enlarged, lumpy margin