Module 4 Medications

Question 1

Attenuated (Live) Vaccine

Answer 1

• Ex: Measles, mumps and rubella Vaccine
• Uses weakened live microbes to stimulate an immune response
• SE: reaction at injection site, flu like symptoms, headache, anaphylaxis

Question 2

Inactivated (Killed) Vacine

Answer 2

• Ex: Hepatitis A virus vaccine
• Uses killed microbe or componet to induce immunity
• SE: reaction at injection site, flu like symptoms, headache, anaphylaxis

Question 3

Recombinant Vaccine

Answer 3

• Ex: Hepatits B vaccine
• Contained lab made viral proteins that induce immunity without infection risk
• SE: reaction at injection site, flu like symptoms, headache, anaphylaxis

Question 4

Toxoid Vaccines

Answer 4

• Ex: Tetanus vaccine
• Contains inactivated bacterial toxin to stimulate antibody production
• SE: reaction at injection site, flu like symptoms, headache, anaphylaxis

Question 5

Immunostimulant- Interferons

Answer 5

• Ex: Interferon alfa
• Signals neighboring cells to produce antiviral proteins, boosts immune response
• SE: flu like symptoms, fatigue, bone marrow suppression, hepatotoxicity

Question 6

Immunostimulant- Interleukins

Answer 6

• Ex: Interleukin-2
• Activates immune cells or blocks inflammatory interleukin signaling (depending on use)
• SE: fever, hypotension, edema, cardiac arrest

Question 7

Immunosuppressant

Answer 7

• Ex: Cyclosporine
• Inhibits T-cell activation and immune response
• SE: Nephrotoxicity, hypertension, infection, gum hyperplasia

Question 8

Reverse transcriptase Inhibitors (Nucleoside reverse transcriptase inhibitors)

Answer 8

• Ex: Zidovudine
• Blocks reverse transcriptase, preventing HIV from converting RNA to DNA
• SE: N/V, hepatomegaly, BBW- fatal lactic acidosis with hepatomegaly and steatosis

Question 9

Integrase Strand Transfer Inhibitors

Answer 9

• Ex: Dolutegravir
• Prevents viral DNA from integrating into host genome
• SE: insomnia, headache, hepatoxicity, MI and cytopenias