CODEINE

Question 1

Drug class

Answer 1

opiates

Question 2

How does it work?

Answer 2

1. it is metabolised by the liver to morphine

Question 3

Indications

Answer 3

1. pain

- mild to mod

Question 4

Contra-indications (2)

Answer 4

1. reap disease

2. epilepsy

Question 5

In whom should the dose be reduced in? (3)

Answer 5

1. elderly
2. renal impairment
3. hepatic impairment

Question 6

Side effects (4)

Answer 6

1. GI

• nausea
• constipation

2. head

• drowsiness
• dizziness

3. neurological
   - depression
4. resp
   - depression

Question 7

Why should you not give codeine IV?

Answer 7

causes severe anaphylactic reactions

Question 8

Interactions (2)

Answer 8

1. other sedating drugs

• antipsychotics
• tricyclic antidepressants
• benzodiazepines

2. tramadol

Question 9

Elimination

Answer 9

urine