VANCOMYCIN

Question 1

Drug class

Answer 1

glycopeptides

Question 2

How does it work?

Answer 2

inhibits the synthesis of the cell wall of GRAM POSITIVE BACTERIA

Question 3

Indications (2)

Answer 3

• gram positive infections

- antibiotic associated colitis

Question 4

What is an example of a gram positive infection?

Answer 4

endocarditis

Question 5

What is an example of antibiotic associated colitis?

Answer 5

c.difficile

Question 6

Contraindications (2)

Answer 6

DOSE REDUCTION IN:

1. renal impairment
2. elderly

Question 7

Side effects (6)

Answer 7

1. thrombophlebitis
2. Red man syndrome
3. hypersensitivity reaction
4. nephrotoxicity
5. ototoxicity
6. blood disorders - thrombocytopenia and neutropenia

Question 8

What is Red man syndrome?

Answer 8

severe anaphylactic reaction

Question 9

What happens in ototoxicity side effects? (2)

Answer 9

• tinnitus

- hearing loss

Question 10

Interactions (3)

Answer 10

CAUSES NEPHROTOXICITY OR OTOTOXICITY

1. aminoglycosides
2. loop diuretics
3. ciclosporin

Question 11

What is ciclosporin?

Answer 11

immunosuppressant

Question 12

elimination

Answer 12

urine