LEVITARACETAM

Question 1

Drug class

Answer 1

anti-convulsant

Question 2

How does it work? (5)

Answer 2

1. binds to synaptic vesicle glycoprotein
2. inhibits pre-synaptic calcium channels
3. reduces neurotransmitter release
4. acts a neuromodulator
5. stops conduction across synapses

Question 3

Indications

Answer 3

1. epilepsy

Question 4

Contra-indications (5)

Answer 4

1. pregnancy
2. elderly
3. kids
4. kidney impairment
5. liver impairment

Question 5

Side effects (4)

Answer 5

1. CNS effects

• sleepy
• decreased energy
• headache
• dizziness
• coordination difficulties

2. neuropsychiatric symptoms

• anxiety
• apathy
• agitation
• emotionally labile
• depression

3. skin reactions

• Steven Johnson’s syndrome
• Toxic epidermis necrolysis

4. suicide

Question 6

Interactions

Answer 6

none

Question 7

Elimination

Answer 7

urine