ENOXAPARIN

Question 1

Drug class

Answer 1

LMWH - heparin

Question 2

How does it work? (2)

Answer 2

1. inhibits the function of factor Xa and thrombin

2. this prevents the formation of the fibrin clot

Question 3

Indications (2)

Answer 3

1. vessels
   - venous thrombus embolism (VTE)
2. heart
   - ACS

Question 4

Contra-indications (6)

Answer 4

1. clotting

• clotting disorders
• anti-coagulants

2. surgery and invasive procedure

• spinal anaesthesia
• lumbar puncture

3. trauma
4. renal impairment
   - use lower dose
5. severe uncontrolled hypertension

Question 5

Side effects (3)

Answer 5

1. bleeding
2. injection site reactions
3. thrombocytopenia
   - induced by heparin

Question 6

Interactions (2)

Answer 6

1. anti-thrombotic drugs
2. anti-platelets drugs

increases risk of bleeding

Question 7

Elimination

Answer 7

kidneys