asthma

Question 1

2 extra function of lung vessels

Answer 1

1. filter out infections

2. act as reservoir for extra blood

Question 2

what is hereditary hemorrhagic telantectagia

Answer 2

arteries connect to veins without hitting microscirculation

Question 3

what is likely cause of HHT

Answer 3

TGF-beta system

Question 4

what produces surfactant

Answer 4

type 2 pneumocytes

Question 5

treatment of lack of sufactant

Answer 5

corticosteroids in utero

Question 6

what happens if too much surfactant

Answer 6

pulmonary alveolar proteinosis

Question 7

what can help with pulmonary hypertension

Answer 7

NO - vasodilate to match perfusion to ventilation

Question 8

what does a1 antitrypsin do, and what happens if missing?

Answer 8

protease inhibitor - if not, get proteases and breaks down elastase– early emphysema

Question 9

2 methods of lung infection defence

Answer 9

1. bronchus lymphoid tissues

2. alveolar macrophages

Question 10

what does immunity development depend on?

Answer 10

whether we are expose to bacteria

Question 11

3 other functions of biome

Answer 11

1. diabetes and obesity
2. gut health
3. replacement of bad bact. by good

Question 12

what defines asthma as a SYNDROME

Answer 12

1. bronchospasm
2. mucous hypersecretion
3. epithelial desquamination
4. airway inflammation

Question 13

what is a pulmonary dendritic cell

Answer 13

small sub-endothelial cell

antigen presenting

Question 14

what are 2 lung lymphocyte cell types and fucntions

Answer 14

1. Th1 - regulate immunity

2. Th2 - active in allergic disease

Question 15

which lymphocyte dominates in childhood

Answer 15

Th1 - infections

Question 16

what is possible end result for asthma

Answer 16

lung fibrosis

Question 17

what happens to lymphocytes in asthma

Answer 17

no infections = Th1 and Th2 imbalance