Exam

Question 1

Beta receptors

Answer 1

1 - heart - ionotpe, chronotrope - cAMP up

2. smooth muscle dilation - bronchodilation

Question 2

Alpha receptors

Answer 2

1. smooth muscle contraction - skin, GI

2. smooth muscle mixed effects -cAMP down

Question 3

Channel openings in auto cells

Answer 3

1. Na open
2. Na close - K fast open
3. K fast close, Ca open, K slow close
4. K close and repolarized

Question 4

Drugs stim. smooth muscle contraction and dilation and how

Answer 4

contraction: alpha-1: nor-epin, angiotensin, endothelin - PLC to IP3 receptors
dilation: beta-2: epi - via cAMP phosphoylation of MLCK