Eso CA

Question 1

2 types of espophaeal

Answer 1

1. SCC - from squam epi

2. adenocarcinoma - from columnar epi

Question 2

epi

Answer 2

• uncommon
• male>femal
• > 60
• regional

Question 3

how is epi changing

Answer 3

SSC on decline

adeno on the rise

Question 4

location and precursor to adeno

Answer 4

location: distal
precursor: barrets

Question 5

location and precursor to SCC

Answer 5

location: mid
precursor: squamous dysplasia

Question 6

what is morpho of 2 types

Answer 6

SCC- solid with no glands

adeno - look for glandular spaces

Question 7

what is target for screening

Answer 7

barretts

Question 8

SCC risk factors

Answer 8

1. alc
2. smoking
3. low SES
4. male
5. AA
6. diet
7. past HandN CA

Question 9

Adeno risk factors

Answer 9

1. reflux
2. barrets
3. older
   4, male
4. obese
5. smoker
6. white

Question 10

clinical features

Answer 10

1. dysphagia
2. odynophagia
3. anorexia
4. ussualy advanced when seen

Question 11

outcomes for surg

Answer 11

for local disease
- high complication rate
-

Question 12

** 3 keys to resctability

Answer 12

no
1. nodes
2, mets
3. invasion of adjacent organs

Question 13

what to do for non-resectable (2)

Answer 13

1. combined chemo/rad

2. stent for palliation

Question 14

pronosis

Answer 14

resectable : node+ - 17, - 40

nonresectable: 3-5