Lymphoid

Question 1

2 main lymph organs of early life

Answer 1

1. thymus

2. bone marrow

Question 2

2 main different lymphocytes and what they do

Answer 2

B - respond to specific antigen with antibody

T - some attack antigens and others regulate responses

Question 3

2 main types of lymph tissues and where

Answer 3

1. Primary - marrow and thymus

2. secondary - diffuse, spleen, lymph nodes

Question 4

Path of t-cell dev.

Answer 4

marrow> thymus where devs. antigen receptor>periphery

Question 5

path of B-cell dev.

Answer 5

marrow>dev. immucometence>periphery

Question 6

2 main parts of thymus

Answer 6

cortex - dark with many small lymphocytes

medulla - lighter with fewer lymphocytes

Question 7

cells that line the capsule

Answer 7

epithelioreticular cells

• connect by desmosomes
• creates blood thymus barrier

Question 8

fate of T-lymphocytes in thymus

Answer 8

5% dev. proper T-cell receptor, the rest are apop and macrophaged

Question 9

what divides the lobules in thymus

Answer 9

trabeculae

Question 10

what are hassal’s corpuscles

Answer 10

large centers that fill up with keratin

Question 11

3 types of diffuse lymph tissue

Answer 11

1. lymph nodules - germinal centers where activated lymph differentiate
2. tonsils - encapsulade in pharynx
3. peyer’s patches - in illeum

Question 12

features of lymph nodes

Answer 12

• fibrous capsule with penetrating trabeculae
• sinuses where afferent lymph dumped
• dendritic cells are antigen presenters
• medulary cords - with T and B and plasmas

Question 13

what is special about post-capillary venules

Answer 13

• lined with cuboidal cells instead of squamous

- tells lymph to leave blood and enter node

Question 14

features of spleen

Answer 14

• detect and respond to blood born antigens

- remove old RBCs and platelets

Question 15

2 types of spleen tissue

Answer 15

1. white pulp - central arteries with T and B lymphocytes

2. Red pulp - splenic sinuses - arterioles, RBCs, macrophages, and reticular cells

Question 16

where do vessels travel in spleen

Answer 16

in trabeculae

Question 17

what surrounds arteries in spleen

Answer 17

periareriole sheath - with lymphocytes

Question 18

make-up of sinusoid

Answer 18

spindle endothelial cells with broken up basement membrane